Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | DAPK1 | P53355 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14045897 | 0.89 | MAOA (0.44) | MAPTMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL12713379 | 0.89 | MAOA (0.44) | MAPTMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL20978684 | 0.88 | ADORA2A (0.40) | MAPTMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL13154627 | 0.87 | SOS1 (0.36) | MAPTMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL27321737 | 0.85 | MEN1 (0.42) | MAPTMAOAMEN1KMT2ADAPK1 | |
| SCHEMBL8171745 | 0.84 | EGFR (0.48) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL13444092 | 0.84 | EGFR (0.48) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL497017 | 0.84 | MAPT (0.40) | MAPTMAOAMEN1KMT2ADAPK1 | |
| SCHEMBL10789834 | 0.84 | MAPT (0.40) | MAPTMAOAMEN1KMT2ADAPK1 | |
| SCHEMBL19037043 | 0.82 | MEN1 (0.41) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021102404-A1 | LUNG TARGETED ANTICANCER THERAPIES WITH LIPOSOMAL ANNAMYCIN | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-05-27 | — | — | WO | disclosed |
| WO-2020264161-A1 | METHOD OF RECONSTITUTING LIPOSOMAL ANNAMYCIN | PICKER DONALD (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020264160-A1 | PREPARATION OF PRELIPOSOMAL ANNAMYCIN LYOPHILIZATE | PICKER DONALD (US) | 2020-12-30 | — | — | WO | disclosed |