Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17428797 | 0.84 | ATM (0.43) | ATMADAM10MMP2MMP9CYP2C19 | |
| SCHEMBL22831693 | 0.78 | CYP2D6 (0.46) | ATMALDH1A1MAPK1CYP2C19 | |
| SCHEMBL28152017 | 0.76 | ATM (0.42) | ATMALDH1A1MAPK1CYP2C19 | |
| SCHEMBL16300573 | 0.72 | PEPD (0.37) | ATMADAM10MMP2MMP9 | |
| SCHEMBL16349111 | 0.72 | PEPD (0.37) | ATMADAM10MMP2MMP9 | |
| SCHEMBL20139362 | 0.70 | GRM2 (0.32) | ALDH1A1MAPK1CYP2C19 | |
| SCHEMBL20139363 | 0.70 | GRM2 (0.32) | ALDH1A1MAPK1CYP2C19 | |
| SCHEMBL25364146 | 0.70 | GRM2 (0.36) | CYP2C19 | |
| SCHEMBL21806853 | 0.70 | GRM2 (0.36) | CYP2C19 | |
| SCHEMBL16300561 | 0.69 | PEPD (0.33) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264120-A1 | PI3KGAMMA INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-30 | — | — | WO | disclosed |