SCHEMBL22845242

SCHEMBL22845242

c1ccc(-c2nc(-c3ccc(-c4cccc(-c5cccc6c5sc5ccccc56)c4)cc3)nc(-n3c4ccccc4c4ccccc43)n2)cc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.48
PRKDC P78527 6/20 0.38
LIMK1 P53667 4/20 0.33
PIK3CD O00329 2/20 0.33
PIK3CB P42338 2/20 0.33
PARP14 Q460N5 1/20 0.33
PIM3 Q86V86 1/20 0.33
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
DNPH1 O43598 1/20 0.33
MAP3K8 P41279 3/20 0.32
MAPT P10636 1/20 0.32
BRD4 O60885 1/20 0.32
PIK3CA P42336 1/20 0.32
MTOR P42345 1/20 0.32
PIK3CG P48736 1/20 0.32
KCNH2 Q12809 1/20 0.32
BRDT Q58F21 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15294013 0.97 ALOX5 (0.46) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL25661336 0.97 ALOX5 (0.49) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL24303306 0.96 ALOX5 (0.45) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL24303469 0.96 ALOX5 (0.45) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL18353189 0.96 ALOX5 (0.45) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL15293994 0.96 ALOX5 (0.46) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL14979345 0.96 ALOX5 (0.46) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL21964848 0.95 ALOX5 (0.47) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL25661521 0.95 ALOX5 (0.46) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL22845390 0.94 ALOX5 (0.42) ALOX5PRKDCLIMK1MAP3K8PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284470-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT COMPOUND DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-09-07 US disclosed
US-20230284470-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT COMPOUND DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-09-07 US disclosed
US-20200407348-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200407348-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD1, OXER1, OCIAD2 ALOX5 285/4885PRKDC 2766/4885LIMK1 96/4885
US-20230284470-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT COMPOUND OR10J3, ICOSLG, L1CAM ALOX5 755/4885PRKDC 1696/4885LIMK1 239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.