Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 12/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2285550 | 0.87 | CYP3A4 (0.50) | CYP3A4NAMPTSYKKMT2APKM | |
| SCHEMBL1186455 | 0.86 | ATM (0.55) | SYKKMT2AATMMEN1GAA | |
| SCHEMBL3825012 | 0.86 | ATM (0.55) | SYKKMT2AATMMEN1GAA | |
| SCHEMBL825959 | 0.86 | ATM (0.55) | SYKKMT2AATMMEN1GAA | |
| SCHEMBL30718545 | 0.85 | CYP17A1 (0.47) | CYP3A4SYKKMT2AANPEPERAP2 | |
| SCHEMBL13821709 | 0.84 | CYP3A4 (0.54) | CYP3A4NAMPTSYKKMT2APKM | |
| SCHEMBL30191579 | 0.81 | CYP3A4 (0.46) | CYP3A4KMT2APKMTBXAS1ANPEP | |
| SCHEMBL22035309 | 0.81 | CYP3A4 (0.46) | CYP3A4KMT2APKMTBXAS1ANPEP | |
| SCHEMBL479037 | 0.81 | ACE (0.61) | CYP3A4 | |
| SCHEMBL479035 | 0.81 | ACE (0.61) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260008758-A1 | LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED | 2026-01-08 | — | — | US | disclosed |
| US-20110207783-A1 | RENIN INHIBITORS | MERCK CANADA INC. (CA) | 2011-08-25 | — | — | US | disclosed |
| EP-2188256-A1 | RENIN INHIBITORS | Merck Frosst Canada Ltd. (CA) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009018662-A9 | RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2010-04-08 | — | — | WO | disclosed |
| WO-2009018662-A1 | RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2009-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207783-A1 | RENIN INHIBITORS | REN, ACE, AGT | CYP3A4 732/4885NAMPT 983/4885SYK 4174/4885 |
| US-20260008758-A1 | LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | DPP3, DPP7, DPP9 | CYP3A4 655/4885NAMPT 4069/4885SYK 4077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.