Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.31 |
| ▸ | PRLHR | P49683 | 2/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22845508 | 1.00 | USP7 (0.32) | USP7STAT3GRM1PRLHRPARP1 | |
| SCHEMBL24173491 | 0.91 | ITGB2 (0.33) | PRLHRPARP1PARP2 | |
| SCHEMBL22845357 | 0.90 | PRLHR (0.35) | PRLHR | |
| SCHEMBL22845502 | 0.86 | GRM1 (0.34) | USP7GRM1PARP1 | |
| SCHEMBL24173941 | 0.85 | GRM1 (0.39) | USP7GRM1 | |
| SCHEMBL22845444 | 0.83 | MAPT (0.34) | GRM1 | |
| SCHEMBL22845232 | 0.82 | GRM1 (0.34) | GRM1 | |
| SCHEMBL22845278 | 0.82 | GRM5 (0.32) | USP7GRM1 | |
| SCHEMBL22845442 | 0.81 | GRM5 (0.34) | GRM1 | |
| SCHEMBL22845201 | 0.81 | S1PR2 (0.33) | USP7GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820773-B2 | Tricyclic compounds | ALIGOS THERAPEUTICS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-11820773-B2 | Tricyclic compounds | ALIGOS THERAPEUTICS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| WO-2022115384-A1 | TRICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2022-06-02 | — | — | WO | disclosed |
| US-20220000874-A1 | TRICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2022-01-06 | — | — | US | disclosed |
| US-11136321-B2 | Tricyclic compounds | ALIGOS THERAPEUTICS, INC. (US) | 2021-10-05 | — | — | US | disclosed |
| US-20200407361-A1 | TRICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2020-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220000874-A1 | TRICYCLIC COMPOUNDS | SLC10A1, PKD1, CEL | USP7 3629/4885STAT3 754/4885GRM1 4264/4885 |
| US-11136321-B2 | Tricyclic compounds | SLC10A1, PKD1, CEL | USP7 3629/4885STAT3 754/4885GRM1 4264/4885 |
| US-11820773-B2 | Tricyclic compounds | SLC10A1, PKD1, CEL | USP7 3629/4885STAT3 754/4885GRM1 4264/4885 |
| US-20200407361-A1 | TRICYCLIC COMPOUNDS | SLC10A1, PKD1, CEL | USP7 3629/4885STAT3 754/4885GRM1 4264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.