Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.53 |
| ▸ | HPGD | P15428 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | PKM | P14618 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | GAA | P10253 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | CASP1 | P29466 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | CASP7 | P55210 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444835 | 0.74 | CYP1A2 (0.54) | KDM4EALDH1A1HPGDMAPTPKM | |
| SCHEMBL6440596 | 0.72 | KDM4E (0.42) | KDM4EALDH1A1HPGDMAPTPKM | |
| SCHEMBL1911795 | 0.72 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPTPKM | |
| SCHEMBL6446348 | 0.71 | KDM4E (0.47) | KDM4EALDH1A1HPGDMAPTPKM | |
| SCHEMBL22579091 | 0.70 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDMAPTPKM | |
| SCHEMBL21722540 | 0.70 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDMAPTPKM | |
| SCHEMBL6252591 | 0.69 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDMAPTPKM | |
| SCHEMBL1176596 | 0.69 | KDM4E (0.42) | KDM4EALDH1A1HPGDMAPTPKM | |
| SCHEMBL6441332 | 0.69 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDMAPTPKM | |
| SCHEMBL21814372 | 0.68 | ADORA2A (0.48) | ADORA2AADORA1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020263058-A1 | AMINOCYANOPYRIDINE DERIVATIVE AND USE THEREOF | 한미약품 주식회사 | 2020-12-30 | — | — | WO | disclosed |