Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998838 | 0.87 | KDM4E (0.37) | HSP90AA1KDM4ELMNATP53ALOX15 | |
| SCHEMBL21952695 | 0.84 | CCR1 (0.50) | HSP90AA1KDM4ELMNATP53ALOX15 | |
| SCHEMBL30395826 | 0.79 | CCR1 (0.50) | HSP90AA1KDM4ELMNATP53ALOX15 | |
| SCHEMBL23060442 | 0.79 | CCR1 (0.50) | HSP90AA1KDM4ELMNATP53ALOX15 | |
| SCHEMBL24399703 | 0.79 | LIMK1 (0.40) | HSP90AA1KDM4ELMNATP53ALOX15 | |
| SCHEMBL9486107 | 0.77 | KDM4E (0.50) | HSP90AA1KDM4ELMNATP53ALOX15 | |
| SCHEMBL1901071 | 0.77 | KDM4E (0.46) | HSP90AA1KDM4ELMNATP53ALOX15 | |
| SCHEMBL18544788 | 0.73 | CCR1 (0.39) | HSP90AA1KDM4ELMNATP53ALOX15 | |
| SCHEMBL23618573 | 0.73 | ADORA2A (0.42) | HSP90AA1KDM4ELMNATP53ALOX15 | |
| SCHEMBL24616830 | 0.73 | ALDH1A1 (0.35) | KDM4ELMNAALDH1A1ADORA3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020263703-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |