SCHEMBL22848232

SCHEMBL22848232

Cc1cc(C)c2ccccc2c1N1/C(=C\C=C2C(=O)c3cc4ccccc4cc3C2=O)C2(CCCCC2)c2c1ccc1ccccc21

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22848219 0.93 KDM4E (0.31) KDM4EALDH1A1LMNAGLAGAA
SCHEMBL22849283 0.89 ATM (0.31) ALDH1A1
SCHEMBL22848447 0.87
SCHEMBL22848246 0.85 HSP90AA1 (0.34) KDM4EALDH1A1LMNAGLAGAA
SCHEMBL22848228 0.82
SCHEMBL22848456 0.81 TP53 (0.31) MAPT
SCHEMBL22848199 0.81
SCHEMBL22848467 0.81 MAPT (0.32) KDM4EALDH1A1LMNAGLAGAA
SCHEMBL22848164 0.79 PRMT1 (0.37) KDM4EALDH1A1LMNAGLAGAA
SCHEMBL22848216 0.79 ATM (0.32) KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171165-B2 Photoelectric conversion element, imaging element, optical sensor comprising a photoelectric conversion film containing a predetermined compound, and compound FUJIFILM CORPORATION (JP) 2021-11-09 US disclosed
US-20200411569-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-31 US disclosed