SCHEMBL22848246

SCHEMBL22848246

O=C1C(=C/C=C2\N(c3ccc4ccccc4c3)c3ccc4ccccc4c3C23CCCCC3)C(=O)c2cc3ccccc3cc21

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.34
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
HPGD P15428 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PMM2 O15305 1/20 0.31
MPI P34949 1/20 0.31
PHOSPHO1 Q8TCT1 1/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22848202 0.88 POLB (0.31) POLB
SCHEMBL22848447 0.86
SCHEMBL22848232 0.85 KDM4E (0.31) ALDH1A1LMNAHPGDKDM4EGLA
SCHEMBL22848219 0.85 KDM4E (0.31) ALDH1A1LMNAHPGDKDM4EGLA
SCHEMBL22849275 0.83 PRMT1 (0.38) HSP90AA1ALDH1A1LMNAHPGDCYP1A2
SCHEMBL22849283 0.83 ATM (0.31) ALDH1A1POLB
SCHEMBL22848201 0.82 POLB (0.31) POLB
SCHEMBL22848428 0.78 CYP1B1 (0.33) ALDH1A1
SCHEMBL22848496 0.76 HSP90AA1 (0.36) HSP90AA1ALDH1A1LMNAHPGDCYP1A2
SCHEMBL22848434 0.76 PRMT1 (0.38) ALDH1A1LMNAHPGDCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171165-B2 Photoelectric conversion element, imaging element, optical sensor comprising a photoelectric conversion film containing a predetermined compound, and compound FUJIFILM CORPORATION (JP) 2021-11-09 US disclosed
US-20200411569-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-31 US disclosed