Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29614787 | 0.80 | KRAS (0.42) | KRAS | |
| SCHEMBL22848275 | 0.80 | KRAS (0.42) | KRAS | |
| SCHEMBL22848184 | 0.77 | KRAS (0.40) | KRAS | |
| SCHEMBL22848351 | 0.74 | KRAS (0.48) | KRAS | |
| SCHEMBL22848336 | 0.74 | KRAS (0.45) | KRAS | |
| SCHEMBL23234919 | 0.73 | KRAS (0.57) | KRAS | |
| SCHEMBL25886926 | 0.73 | KRAS (0.35) | KRAS | |
| SCHEMBL31053009 | 0.72 | KRAS (0.36) | KRAS | |
| SCHEMBL23415210 | 0.71 | KRAS (0.61) | KRAS | |
| SCHEMBL29593106 | 0.71 | KRAS (0.61) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020259513-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF KRAS G12C | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2020-12-30 | — | — | WO | disclosed |