Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GLP1R | P43220 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22527258 | 1.00 | TSHR (0.57) | TSHRRECQLFAAHACHEALDH1A1 | |
| SCHEMBL22525311 | 1.00 | TSHR (0.57) | TSHRRECQLFAAHACHEALDH1A1 | |
| SCHEMBL11840937 | 0.96 | TSHR (0.61) | TSHRRECQLFAAHACHEALDH1A1 | |
| SCHEMBL19168532 | 0.96 | TSHR (0.56) | TSHRRECQLFAAHACHEALDH1A1 | |
| SCHEMBL25123583 | 0.95 | FAAH (0.53) | TSHRRECQLFAAHACHEGLP1R | |
| SCHEMBL23945978 | 0.91 | FAAH (0.57) | TSHRRECQLFAAHGLP1R | |
| SCHEMBL23945963 | 0.91 | FAAH (0.57) | TSHRRECQLFAAHGLP1R | |
| SCHEMBL25654294 | 0.91 | FAAH (0.56) | TSHRRECQLFAAHACHE | |
| SCHEMBL25126005 | 0.89 | TSHR (0.48) | TSHRRECQLFAAHACHEGLP1R | |
| SCHEMBL30374444 | 0.89 | TSHR (0.48) | TSHRRECQLFAAHACHEGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264499-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |