Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16625968 | 0.89 | PIK3CD (0.45) | PIK3CDTSHRKDM4E | |
| SCHEMBL22906407 | 0.86 | PIK3CD (0.36) | PIK3CDTSHR | |
| SCHEMBL22856343 | 0.86 | PIK3CD (0.38) | PIK3CDTSHR | |
| SCHEMBL16625956 | 0.83 | PIK3CD (0.44) | PIK3CDTSHR | |
| SCHEMBL23945632 | 0.81 | PIK3CD (0.57) | PIK3CD | |
| SCHEMBL22790819 | 0.81 | PIK3CD (0.57) | PIK3CD | |
| SCHEMBL11932513 | 0.81 | PIK3CD (0.42) | PIK3CDTSHRKDM4E | |
| SCHEMBL25888495 | 0.81 | PIK3CD (0.57) | PIK3CD | |
| SCHEMBL23221024 | 0.79 | ADH1C (0.43) | KDM4E | |
| SCHEMBL11932511 | 0.79 | PIK3CD (0.41) | PIK3CDTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4328219-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022125790-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |
| WO-2020264499-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |