ADH1C

Alcohol dehydrogenase 1C · P00326 · ADH1C on Sugi Atlas →

21,894 patent compounds predicted against ADH1C, 10,668 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL39255 SCHEMBL39255 0.94 11/20
SCHEMBL59918 SCHEMBL59918 0.41 10/20
SCHEMBL329469 SCHEMBL329469 0.41 10/20
SCHEMBL493755 SCHEMBL493755 0.41 10/20
SCHEMBL536191 SCHEMBL536191 0.59 9/20
SCHEMBL528874 SCHEMBL528874 0.52 9/20
SCHEMBL411186 SCHEMBL411186 0.46 7/20
SCHEMBL303776 SCHEMBL303776 1.00 5/20
SCHEMBL15013 SCHEMBL15013 0.50 5/20
SCHEMBL283931 SCHEMBL283931 0.50 5/20
SCHEMBL612785 SCHEMBL612785 0.50 5/20
SCHEMBL612962 SCHEMBL612962 0.50 5/20
SCHEMBL245391 SCHEMBL245391 1.00 4/20
SCHEMBL277123 SCHEMBL277123 1.00 4/20
SCHEMBL277517 SCHEMBL277517 1.00 4/20
SCHEMBL645299 SCHEMBL645299 1.00 4/20
SCHEMBL277250 SCHEMBL277250 0.96 4/20
SCHEMBL302803 SCHEMBL302803 0.61 4/20
SCHEMBL276438 SCHEMBL276438 0.59 4/20
SCHEMBL304406 SCHEMBL304406 0.57 4/20

Clinical trials — most relevant to ADH1C by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Late Effects of Ethanol Intake on the Glucose Response to Subcutaneous Glucagon in Type 1 Diabetes PHASE4COMPLETED
Predicting Alcoholics' Treatment Responses to a Selective Serotonin Re-uptake Inhibitor (SSRI) PHASE2COMPLETED
Clinical Trial Characterizing the Bioavailability of 1-Octanol in Adults With Ethanol-responsive Essential Tremor PHASE2COMPLETED
Pharmacogenetic Study of Ondansetron in Alcohol Use Disorder PHASE2COMPLETED
Non-oxidative Metabolite Profiles After Increasing Doses of Ethanol PHASE1COMPLETED
Phase I, Dose-Escalation Study of Dihydromyricetin (DHM) to Treat Alcohol-Associated Liver Disease PHASE1NOT_YET_RECRUITING
Nicotinic Receptor Genetic Variation and Alcohol Reward PHASE1RECRUITING
ALDH2 Genetic Testing in East Asian Community nanNOT_YET_RECRUITING
ALDH2 Single Nucleotide Polymorphisms and Prognosis of Esophageal Cancer Patients nanRECRUITING
Moderate Alcohol Consumption, Risk of Cardiovascular Disease and Type 2 Diabetes: Influence of Alcohol Oxidation nanCOMPLETED
Alcohol Metabolism and Disease Risk in Asians nanCOMPLETED
Environmental and Biological Monitoring Pilot Study for Polycyclic Aromatic Hydrocarbons in Linxian, China nanCOMPLETED
Bipolar Disorder With Alcoholism in Han Chinese nanUNKNOWN
Validation in Humans of Genes Involved in Alcohol Drinking, Stress-Induced Alcohol Drinking and Relapse nanCOMPLETED
Adrenoleukodystrophy National Registry Study nanRECRUITING
Hepatic Lipid Metabolism-Alcohol Use Disorder nanRECRUITING
Dose-response Effect of Alcohol Ingestion on Steroid Profile nanCOMPLETED
Endophenotyping With Functional Magnetic Resonance Imaging (fMRI) nanCOMPLETED
Alcoholic Liver Disease and the Gut Microbiome nanACTIVE_NOT_RECRUITING
Alcohol Consumption and Circulating Metabolites nanCOMPLETED
Biobehavioral Pathways Underlying Alcohol Use and Health nanCOMPLETED
Dissecting the Genetics of Fetal Alcohol Spectrum Disorders nanCOMPLETED
Understanding Genetic Risk for Alcohol Use Disorder nanCOMPLETED
Clinical-Genetic Variation in GABA/Alcohol Sensitivity nanCOMPLETED
Pharmacogenetic Profiling of Antipsychotics-Induced X-Syndrome and Diabetes (PAXD) nanUNKNOWN
Influence of Age and Sex on Alcohol Metabolism and Acute Responses nanCOMPLETED
Learning and Relapse Risk in Alcohol Dependence nanCOMPLETED
The Genetic Basis for Vulnerability to Substance Abuse nanCOMPLETED
Acamprosate: Genes Associated With Response nanCOMPLETED
Genetic and Neural Factors in Alcohol-Related Cognition nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ADH1C binder may also engage these)

ProteinNameSimilarity
P00328 1.000 P00328 →
O97959 1.000 O97959 →
Q5R1W2 1.000 Q5R1W2 →
ADH1A Alcohol dehydrogenase 1A 1.000 landscape →
P14139 1.000 P14139 →
P86885 1.000 P86885 →
P00329 1.000 P00329 →
P80338 1.000 P80338 →
Q64415 1.000 Q64415 →
P19631 1.000 P19631 →
ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 1.000 landscape →
P23991 1.000 P23991 →
Q5RBP7 1.000 Q5RBP7 →
Q03505 1.000 Q03505 →
P00327 1.000 P00327 →
P49645 1.000 P49645 →
P28469 1.000 P28469 →
P80512 1.000 P80512 →
P80222 1.000 P80222 →
O19053 1.000 O19053 →
P22797 1.000 P22797 →
P41680 1.000 P41680 →
Q3ZC42 1.000 Q3ZC42 →
P86883 1.000 P86883 →
P19854 1.000 P19854 →
Q64437 1.000 Q64437 →
P28474 1.000 P28474 →
Q9Z2M2 1.000 Q9Z2M2 →
P81601 1.000 P81601 →
P93629 1.000 P93629 →