Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 2/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22836449 | 1.00 | HTR2A (0.47) | HTR2AHTR2CHTR2BSCN1ASCN5A | |
| SCHEMBL26352717 | 1.00 | HTR2A (0.47) | HTR2AHTR2CHTR2BSCN1ASCN5A | |
| SCHEMBL22835504 | 0.90 | MAOA (0.53) | HTR2AHTR2CHTR2BSCN1ASCN5A | |
| SCHEMBL31533425 | 0.90 | HTR2A (0.55) | HTR2AHTR2CHTR2BSCN1ASCN5A | |
| SCHEMBL24607464 | 0.79 | SCN1A (0.40) | SCN1ASCN5ASCN9AMAOA | |
| SCHEMBL29502309 | 0.79 | SCN1A (0.40) | SCN1ASCN5ASCN9AMAOA | |
| Trifluoroacetic Acid SCHEMBL31438769 | 0.76 | HTR2A (0.46) | HTR2AHTR2CHTR2BSCN1ASCN5A | |
| SCHEMBL22835245 | 0.75 | SCN1A (0.38) | SCN1ASCN5ASCN9AALDH1A1MAOA | |
| SCHEMBL22836453 | 0.75 | SCN1A (0.38) | SCN1ASCN5ASCN9AALDH1A1MAOA | |
| SCHEMBL29502492 | 0.75 | SCN1A (0.38) | SCN1ASCN5ASCN9AALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264499-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |