Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 16/20 | 0.84 |
| ▸ | ST14 | Q9Y5Y6 | 16/20 | 0.84 |
| ▸ | TMPRSS2 | O15393 | 14/20 | 0.84 |
| ▸ | HGFAC | Q04756 | 14/20 | 0.84 |
| ▸ | F2 | P00734 | 14/20 | 0.84 |
| ▸ | F10 | P00742 | 5/20 | 0.84 |
| ▸ | MC4R | P32245 | 3/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31593144 | 1.00 | HPN (0.84) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL22849994 | 1.00 | HPN (0.84) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593121 | 1.00 | HPN (0.84) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593103 | 1.00 | HPN (0.84) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593107 | 0.91 | HPN (0.85) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593146 | 0.91 | HPN (0.83) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593152 | 0.91 | HPN (0.83) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593114 | 0.90 | HPN (0.84) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593094 | 0.81 | HPN (0.83) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593139 | 0.81 | HPN (0.83) | HPNST14TMPRSS2HGFACF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264187-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER, VIRAL INFECTIONS, AND ALLERGIC CONDITIONS | JANETKA JAMES (US) | 2020-12-30 | — | — | WO | disclosed |