Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 16/20 | 0.83 |
| ▸ | ST14 | Q9Y5Y6 | 16/20 | 0.83 |
| ▸ | TMPRSS2 | O15393 | 14/20 | 0.83 |
| ▸ | HGFAC | Q04756 | 14/20 | 0.83 |
| ▸ | F2 | P00734 | 14/20 | 0.77 |
| ▸ | F10 | P00742 | 5/20 | 0.77 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.48 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.48 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.48 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31593139 | 1.00 | HPN (0.83) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593124 | 0.96 | HPN (0.84) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593133 | 0.96 | HPN (0.84) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593087 | 0.96 | HPN (0.84) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593092 | 0.96 | HPN (0.84) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL22850400 | 0.91 | HPN (0.84) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593138 | 0.91 | HPN (0.84) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593114 | 0.91 | HPN (0.84) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593090 | 0.91 | HPN (0.84) | HPNST14TMPRSS2HGFACF2 | |
| SCHEMBL31593136 | 0.90 | HPN (0.85) | HPNST14TMPRSS2HGFACF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171495-A1 | MUTLI-TARGETED SERINE PROTEASE INHIBITORS FOR TREATMENT OF CANCER AND VIRAL INFECTION | WASHINGTON UNIVERSITY | 2025-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171495-A1 | MUTLI-TARGETED SERINE PROTEASE INHIBITORS FOR TREATMENT OF CANCER AND VIRAL INFECTION | TMPRSS2, PRSS1, PRSS2 | HPN 13/4885ST14 84/4885TMPRSS2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.