Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25735013 | 0.88 | CYP19A1 (0.37) | CYP19A1POLBMEN1KMT2AMIF | |
| SCHEMBL24878799 | 0.85 | CYP19A1 (0.40) | CYP19A1POLBMEN1KMT2AMIF | |
| SCHEMBL22854013 | 0.84 | CYP19A1 (0.39) | CYP19A1POLBMEN1KMT2AMIF | |
| SCHEMBL24878496 | 0.83 | CYP19A1 (0.39) | CYP19A1POLBMEN1KMT2AMIF | |
| SCHEMBL25734932 | 0.76 | MIF (0.39) | MIFHDAC1 | |
| SCHEMBL5998647 | 0.75 | NOTUM (0.41) | CYP19A1MAPT | |
| SCHEMBL19986373 | 0.75 | CYP19A1 (0.40) | CYP19A1POLBHTTATM | |
| SCHEMBL25734930 | 0.74 | GGPS1 (0.45) | HDAC1 | |
| SCHEMBL25735002 | 0.73 | EPHX2 (0.47) | CYP19A1HDAC1 | |
| SCHEMBL25735014 | 0.73 | GGPS1 (0.40) | CYP19A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264505-A1 | POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES | SERINA THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |