Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 4/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21396407 | 0.86 | ATM (0.38) | NPC1RAB9AL3MBTL1ATMPIK3C3 | |
| SCHEMBL10175527 | 0.82 | ATM (0.43) | ATMPIK3C3PRKDCATRPIK3CA | |
| SCHEMBL21256947 | 0.81 | ADRB1 (0.43) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL21256942 | 0.81 | ADRB1 (0.43) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL17642395 | 0.80 | MAPT (0.42) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL21204374 | 0.80 | MAPT (0.42) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL14167561 | 0.80 | MAPT (0.46) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL19863416 | 0.80 | AKR1C3 (0.41) | ALDH1A1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL14167611 | 0.80 | AKR1C3 (0.41) | ALDH1A1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL19863415 | 0.80 | AKR1C3 (0.41) | ALDH1A1RAB9AKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020261294-A1 | NOVEL APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS | MANKIND PHARMA LTD. (IN) | 2020-12-30 | — | — | WO | disclosed |