Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 0.46 |
| ▸ | PIK3R2 | O00459 | 7/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17330717 | 0.91 | PIK3CD (0.47) | PIK3CDPIK3R2OPRM1OPRD1OGFRL1 | |
| SCHEMBL17330623 | 0.91 | PIK3CD (0.47) | PIK3CDPIK3R2OPRM1OPRD1OGFRL1 | |
| SCHEMBL17330820 | 0.88 | OPRM1 (0.48) | PIK3CDPIK3R2OPRM1OPRD1OGFRL1 | |
| SCHEMBL17331031 | 0.87 | PIK3CD (0.45) | PIK3CDPIK3R2OPRM1OPRD1OGFRL1 | |
| SCHEMBL17331032 | 0.87 | PIK3CD (0.45) | PIK3CDPIK3R2OPRM1OPRD1OGFRL1 | |
| SCHEMBL28511263 | 0.87 | PIK3CD (0.49) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17330563 | 0.86 | PIK3CD (0.44) | PIK3CDPIK3R2OPRM1OPRD1OGFRL1 | |
| SCHEMBL17330565 | 0.86 | PIK3CD (0.44) | PIK3CDPIK3R2OPRM1OPRD1OGFRL1 | |
| SCHEMBL17330951 | 0.86 | PIK3CD (0.44) | PIK3CDPIK3R2OPRM1OPRD1OGFRL1 | |
| SCHEMBL22854515 | 0.84 | PIK3R2 (0.47) | PIK3CDPIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142745-B | Casein kinase 1 epsilon inhibitor, pharmaceutical composition and application thereof | 杭州和正医药有限公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-3964512-A1 | CASEIN KINASE 1epsilon INHIBITOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Hangzhou Healzen Therapeutics Co., Ltd. (CN) | 2022-03-09 | — | — | EP | disclosed |
| WO-2020259463-A1 | CASEIN KINASE 1ε INHIBITOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 杭州和正医药有限公司 | 2020-12-30 | — | — | WO | disclosed |