SCHEMBL22855201

SCHEMBL22855201

Cc1cc(C)c(-c2cccc3sc(Nc4c(C)cccc4C)nc23)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 2/20 0.43
MEN1 O00255 8/20 0.42
KMT2A Q03164 8/20 0.42
NPC1 O15118 6/20 0.42
SMN1; SMN2 Q16637 6/20 0.42
LMNA P02545 6/20 0.42
RAB9A P51151 5/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 3/20 0.42
GAA P10253 3/20 0.42
KDM4E B2RXH2 3/20 0.42
PRNP P04156 1/20 0.42
MAPT P10636 5/20 0.41
NFKB1 P19838 2/20 0.41
NFKB2 Q00653 2/20 0.41
RELA Q04206 2/20 0.41
PKM P14618 2/20 0.40
HTT P42858 2/20 0.39
POLB P06746 1/20 0.38
TRPV1 Q8NER1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29470101 1.00 CRHR1 (0.43) CRHR1MEN1KMT2ANPC1SMN1; SMN2
SCHEMBL22855415 0.92 MEN1 (0.38) CRHR1MEN1KMT2ANPC1SMN1; SMN2
SCHEMBL22855220 0.86 NPC1 (0.48) MEN1KMT2ANPC1SMN1; SMN2LMNA
SCHEMBL22855202 0.82 MEN1 (0.39) CRHR1MEN1KMT2ANPC1SMN1; SMN2
SCHEMBL29470130 0.82 MEN1 (0.39) CRHR1MEN1KMT2ANPC1SMN1; SMN2
SCHEMBL22855217 0.82 MEN1 (0.39) CRHR1MEN1KMT2ANPC1SMN1; SMN2
SCHEMBL29470103 0.80 MEN1 (0.46) CRHR1MEN1KMT2ANPC1SMN1; SMN2
SCHEMBL22855228 0.80 MEN1 (0.46) CRHR1MEN1KMT2ANPC1SMN1; SMN2
SCHEMBL22855222 0.79 NPC1 (0.39) MEN1KMT2ANPC1SMN1; SMN2LMNA
SCHEMBL29873269 0.79 NPC1 (0.39) MEN1KMT2ANPC1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3990503-B1 OLEFIN POLYMERIZATION CATALYSTS BEARING A THIAZOLE OR IMIDAZOLE DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-23 EP disclosed
US-12286502-B2 Olefin polymerization catalysts bearing a thiazole or imidazole DOW GLOBAL TECHNOLOGIES LLC (US) 2025-04-29 US disclosed
CN-114127132-B Olefin polymerization catalyst with thiazole or imidazole 陶氏环球技术有限责任公司 2023-06-20 CN disclosed
US-20220259336-A1 OLEFIN POLYMERIZATION CATALYSTS BEARING A THIAZOLE OR IMIDAZOLE DOW GLOBAL TECHNOLOGIES LLC (US) 2022-08-18 US disclosed
CN-114127132-A Olefin polymerization catalyst with thiazole or imidazole 陶氏环球技术有限责任公司 2022-03-01 CN disclosed
WO-2020263790-A1 OLEFIN POLYMERIZATION CATALYSTS BEARING A THIAZOLE OR IMIDAZOLE DOW GLOBAL TECHNOLOGIES LLC (US) 2020-12-30 WO disclosed