SCHEMBL228554

SCHEMBL228554

Fc1ccc2[nH]ccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 1.00
GPR84 Q9NQS5 1/20 0.58
NR4A2 P43354 2/20 0.56
CYP2A6 P11509 2/20 0.56
F7 P08709 1/20 0.56
LTA4H P09960 1/20 0.56
F3 P13726 1/20 0.56
USP2 O75604 1/20 0.56
GAA P10253 1/20 0.56
ALOX15 P16050 1/20 0.56
RAD51 Q06609 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
IMPDH2 P12268 1/20 0.50
IMPDH1 P20839 1/20 0.50
F2 P00734 1/20 0.47
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
TRPA1 O75762 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18805065 1.00 AHR (1.00) AHRGPR84NR4A2CYP2A6F7
Methane SCHEMBL27929619 0.98 AHR (0.95) AHRGPR84NR4A2CYP2A6F7
Cyanide SCHEMBL31107529 0.94 AHR (0.88) AHRGPR84NR4A2CYP2A6F7
Biphenyl SCHEMBL27962699 0.88 AHR (0.78) AHRGPR84NR4A2CYP2A6F7
Ethylamine SCHEMBL28652638 0.88 AHR (0.78) AHRGPR84NR4A2CYP2A6F7
Formic Acid SCHEMBL28143741 0.88 AHR (0.78) AHRGPR84NR4A2CYP2A6F7
Acetic Acid SCHEMBL6512763 0.87 AHR (0.75) AHRGPR84NR4A2CYP2A6F7
Pyridine SCHEMBL28523686 0.85 AHR (0.72) AHRGPR84NR4A2CYP2A6F7
N-Propyl Bromide SCHEMBL28747033 0.85 AHR (0.72) AHRGPR84NR4A2CYP2A6F7
SCHEMBL8185932 0.84 AHR (0.70) AHRGPR84NR4A2CYP2A6F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2409 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119857098-A Application of indole triazole derivative in preparation of drug-resistant candida albicans drug 云南中医药大学 2025-04-22 CN claimed
EP-4526426-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS Danmarks Tekniske Universitet (DK) 2025-03-26 EP claimed
CN-119462613-A Method for synthesizing tosituba phosphate 厦门欧瑞捷生物科技有限公司 2025-02-18 CN claimed
CN-118749522-A Application of 5-fluoroindole compound in preventing and treating kiwi fruit canker 贵州大学 2024-10-11 CN claimed
EP-4175718-B1 INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER UNIV CLAUDE BERNARD LYON (FR) 2024-10-02 EP claimed
CN-110914425-B High Throughput (HTP) genome engineering platform for improving spinosyns 齐默尔根公司 2024-06-25 CN claimed
CN-118125960-A Bisindole 3-ketone compound, application and preparation method thereof 云南农业大学 2024-06-04 CN claimed
CN-118063373-A 3,3' -Bisindole compound and application and preparation method thereof 云南农业大学 2024-05-24 CN claimed
WO-2023222879-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS DANMARKS TEKNISKE UNIVERSITET (DK) 2023-11-23 WO claimed
US-20230175059-A1 COMPOSITIONS AND METHODS FOR SEQUENCING USING POLYMER BRIDGES ILLUMINA, INC. (US) 2023-06-08 US claimed
US-20050075242-A1 Heterocyclic nitrogen-containing activators and catalyst systems for olefin polymerization UNIVATION TECHNOLOGIES, LLC 2005-04-07 US claimed
EP-1517932-A2 HETEROCYCLIC NITROGEN-CONTAINING ACTIVATORS AND CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION Univation Technologies LLC (US) 2005-03-30 EP claimed
EP-1517931-A1 HALOGEN SUBSTITUTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION Univation Technologies, LLC (US) 2005-03-30 EP claimed
US-20040127348-A1 Halogen substituted catalyst system for olefin polymerization UNIVATION TECHNOLOGIES, LLC 2004-07-01 US claimed
WO-2004003037-A1 HALOGEN SUBSTITUTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC. (US) 2004-01-08 WO claimed
WO-2004003032-A2 HETEROCYCLIC NITROGEN-CONTAINING ACTIVATORS AND CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC (US) 2004-01-08 WO claimed
CN-1451002-A Indole derivatives for treating central nervous system disease LUNDBECK & CO AS H (DK) 2003-10-22 CN claimed
WO-1999063092-A9 ROOT-SPECIFIC PROTEIN INVOLVED IN AUXIN TRANSPORT WHITEHEAD BIOMEDICAL INST (US) 2000-04-06 WO claimed
WO-1999063092-A1 ROOT-SPECIFIC PROTEIN INVOLVED IN AUXIN TRANSPORT WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 1999-12-09 WO claimed
CN-1081676-A The indoles and the indazole derivatives that are used for the treatment and the prevention of cerebral disorders, their preparation and application SANKYO CO (JP) 1994-02-09 CN claimed