Pyridine

Pyridine

SCHEMBL28523686

Fc1ccc2[nH]ccc2c1.c1ccncc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.72
NPC1 O15118 2/20 0.47
CYP19A1 P11511 2/20 0.47
CYP17A1 P05093 1/20 0.45
CYP11B1 P15538 1/20 0.45
CYP11B2 P19099 1/20 0.45
GPR84 Q9NQS5 1/20 0.44
NR4A2 P43354 2/20 0.43
CYP2A6 P11509 2/20 0.43
F7 P08709 1/20 0.43
LTA4H P09960 1/20 0.43
F3 P13726 1/20 0.43
USP2 O75604 1/20 0.43
GAA P10253 1/20 0.43
ALOX15 P16050 1/20 0.43
RAD51 Q06609 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
RAB9A P51151 1/20 0.42
GUSB P08236 1/20 0.40
NISCH Q9Y2I1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28212903 0.86 AHR (0.54) AHRNPC1CYP19A1CYP17A1CYP11B1
SCHEMBL228554 0.85 AHR (1.00) AHRNPC1CYP19A1GPR84NR4A2
SCHEMBL18805065 0.85 AHR (1.00) AHRNPC1CYP19A1GPR84NR4A2
Methane SCHEMBL27929619 0.83 AHR (0.95) AHRNPC1CYP19A1GPR84NR4A2
Biphenyl SCHEMBL27962699 0.82 AHR (0.78) AHRNPC1GPR84NR4A2CYP2A6
Cyanide SCHEMBL31107529 0.80 AHR (0.88) AHRNPC1CYP19A1GPR84NR4A2
Pyridine SCHEMBL28517339 0.79 AHR (0.72) AHRNPC1CYP19A1CYP17A1CYP11B1
Pyridine SCHEMBL28523689 0.79 AHR (0.72) AHRNPC1CYP19A1CYP17A1CYP11B1
Acetic Acid SCHEMBL6512763 0.77 AHR (0.75) AHRNPC1GPR84NR4A2CYP2A6
Quinoline SCHEMBL27717739 0.76 AHR (0.62) AHRNPC1CYP19A1GPR84NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112209915-A Method for air oxidation of N-pyridine indoline compounds 宁波大学 2021-01-12 CN disclosed