Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18435766 | 0.94 | ALDH1A1 (0.42) | ALDH1A1DPP4SMN1; SMN2 | |
| SCHEMBL131046 | 0.88 | ALDH1A1 (0.46) | ALDH1A1DPP4SMN1; SMN2 | |
| SCHEMBL20287506 | 0.87 | ALDH1A1 (0.37) | ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28035861 | 0.86 | ALDH1A1 (0.45) | ALDH1A1DPP4SMN1; SMN2 | |
| SCHEMBL21216002 | 0.84 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL20287957 | 0.84 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL18435768 | 0.83 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL19472471 | 0.83 | ALDH1A1 (0.34) | ALDH1A1DPP4 | |
| SCHEMBL22019516 | 0.79 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL20274375 | 0.79 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200405585-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2020-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200405585-A1 | DENTAL COMPOSITION | CBR3, CBR1, PRDX3 | ALDH1A1 2034/4885DPP4 3784/4885SMN1; SMN2 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.