Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 9/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29873429 | 0.86 | KMT2A (0.38) | CRHR1KMT2AALDH1A1HSD17B10GAA | |
| SCHEMBL22855416 | 0.86 | KMT2A (0.38) | CRHR1KMT2AALDH1A1HSD17B10GAA | |
| SCHEMBL22855422 | 0.81 | KDM4E (0.38) | CRHR1KMT2AALDH1A1GAALMNA | |
| SCHEMBL22855673 | 0.80 | KMT2A (0.39) | CRHR1KMT2AALDH1A1GAALMNA | |
| SCHEMBL29501666 | 0.80 | CRHR1 (0.38) | CRHR1KMT2AALDH1A1HSD17B10LMNA | |
| SCHEMBL22833928 | 0.80 | CRHR1 (0.38) | CRHR1KMT2AALDH1A1HSD17B10LMNA | |
| SCHEMBL22855425 | 0.79 | MEN1 (0.45) | CRHR1KMT2AALDH1A1GAALMNA | |
| SCHEMBL22855428 | 0.78 | CRHR1 (0.41) | CRHR1KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL22855654 | 0.78 | CRHR1 (0.35) | CRHR1KMT2AALDH1A1MEN1 | |
| SCHEMBL22855454 | 0.74 | IDH1 (0.33) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020263790-A1 | OLEFIN POLYMERIZATION CATALYSTS BEARING A THIAZOLE OR IMIDAZOLE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-12-30 | — | — | WO | disclosed |