SCHEMBL22856410

SCHEMBL22856410

CCN1CCC(OC(C)CCC(C)C)CC1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25122854 1.00 HRH3 (0.36) HRH3SMN1; SMN2
SCHEMBL23560058 0.86 HRH3 (0.38) HRH3SMN1; SMN2
SCHEMBL25468942 0.86 HRH3 (0.42) HRH3SMN1; SMN2
SCHEMBL23560055 0.86 HRH3 (0.42) HRH3SMN1; SMN2
SCHEMBL23695835 0.86 HRH3 (0.42) HRH3SMN1; SMN2
SCHEMBL739693 0.79 HRH3 (0.41) HRH3SMN1; SMN2
SCHEMBL22566733 0.76 HRH3 (0.39) HRH3SMN1; SMN2
SCHEMBL23945284 0.74 HRH3 (0.36) HRH3SMN1; SMN2
SCHEMBL19123900 0.73 HRH3 (0.40) HRH3SMN1; SMN2
SCHEMBL102108 0.73 HRH3 (0.41) HRH3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020264490-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2020-12-30 WO disclosed