Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786356 | 0.92 | FAAH (0.55) | MEN1KMT2AFAAHEPHX1CASP2 | |
| SCHEMBL8537389 | 0.92 | FAAH (0.55) | MEN1KMT2AFAAHEPHX1CASP2 | |
| SCHEMBL22525938 | 0.91 | MEN1 (0.57) | MEN1KMT2AFAAHEPHX1CASP2 | |
| SCHEMBL24607163 | 0.90 | MEN1 (0.56) | MEN1KMT2AFAAHTSHRALDH1A1 | |
| SCHEMBL24098140 | 0.88 | FAAH (0.68) | MEN1KMT2AFAAHEPHX1CASP2 | |
| SCHEMBL15888717 | 0.88 | FAAH (0.68) | MEN1KMT2AFAAHEPHX1CASP2 | |
| SCHEMBL2719632 | 0.88 | FAAH (0.68) | MEN1KMT2AFAAHEPHX1CASP2 | |
| SCHEMBL2749360 | 0.86 | FAAH (0.65) | MEN1KMT2AFAAHEPHX1CASP2 | |
| SCHEMBL8326097 | 0.85 | TSHR (0.54) | MEN1KMT2AFAAHEPHX1CASP2 | |
| SCHEMBL21765846 | 0.85 | MEN1 (0.94) | MEN1KMT2AFAAHEPHX1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264490-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |