SCHEMBL2285663

SCHEMBL2285663

CCCC[N+]1(CCCC[N+]2(CCCC)CCCC2)CCCC1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2396260 0.97 TSHR (0.35) TSHRLMNATHRB
SCHEMBL898641 0.97 TSHR (0.35) TSHRLMNATHRB
SCHEMBL1884306 0.97 TSHR (0.35) TSHRLMNATHRB
SCHEMBL12926843 0.97 TSHR (0.35) TSHRLMNATHRB
SCHEMBL2283609 0.97 CYP1A2 (0.32) TSHRLMNA
SCHEMBL830522 0.97 TSHR (0.33) TSHRLMNATHRB
SCHEMBL899043 0.95 TSHR (0.40) TSHRLMNATHRB
SCHEMBL5287059 0.95 TSHR (0.40) TSHRLMNATHRB
SCHEMBL5283805 0.95 TSHR (0.40) TSHRLMNATHRB
Bromide SCHEMBL8912382 0.95 TSHR (0.33) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2986559-B1 MOLECULAR SIEVE COK-5 AND ITS SYNTHESIS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-12-05 EP claimed
US-10099934-B2 Molecular sieve, COK-5, its synthesis and use EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-10-16 US claimed
EP-2367761-B1 MOLECULAR SIEVE SSZ-83 CHEVRON USA INC (US) 2016-06-08 EP claimed
EP-2986559-A1 MOLECULAR SIEVE, COK-5, ITS SYNTHESIS AND USE ExxonMobil Chemical Patents Inc. (US) 2016-02-24 EP claimed
US-20160023914-A1 Molecular Sieve, COK-5, Its Synthesis and Use EXXONMOBIL CHEMICAL PATENTS INC. 2016-01-28 US claimed
WO-2014172024-A1 MOLECULAR SIEVE, COK-5, ITS SYNTHESIS AND USE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-10-23 WO claimed
US-7998457-B2 Molecular sieve SSZ-83 CHEVRON U.S.A. INC. (US) 2011-08-16 US claimed
US-20090214418-A1 MOLECULAR SIEVE SSZ-83 CHEVRON U.S.A. INC. 2009-08-27 US claimed
US-20090104112-A1 METHOD FOR MAKING MOLECULAR SIEVE SSZ-83 CHEVRON U.S.A. INC. 2009-04-23 US claimed
EP-3526164-B1 SYNTHESIS OF MOLECULAR SIEVE SSZ-83 CHEVRON USA INC (US) 2020-05-13 EP disclosed
EP-2986559-B1 MOLECULAR SIEVE COK-5 AND ITS SYNTHESIS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-12-05 EP disclosed
US-20180339910-A1 Molecular Sieve, COK-5, Its Synthesis and Use EXXONMOBIL CHEMICAL PATENTS INC. 2018-11-29 US disclosed
US-20180339910-A1 Molecular Sieve, COK-5, Its Synthesis and Use EXXONMOBIL CHEMICAL PATENTS INC. 2018-11-29 US disclosed
US-10099934-B2 Molecular sieve, COK-5, its synthesis and use EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-10-16 US disclosed
US-20090214418-A1 MOLECULAR SIEVE SSZ-83 CHEVRON U.S.A. INC. 2009-08-27 US disclosed
US-20090214418-A1 MOLECULAR SIEVE SSZ-83 CHEVRON U.S.A. INC. 2009-08-27 US disclosed
US-20090214418-A1 MOLECULAR SIEVE SSZ-83 CHEVRON U.S.A. INC. 2009-08-27 US disclosed
US-20090104112-A1 METHOD FOR MAKING MOLECULAR SIEVE SSZ-83 CHEVRON U.S.A. INC. 2009-04-23 US disclosed
US-20090104112-A1 METHOD FOR MAKING MOLECULAR SIEVE SSZ-83 CHEVRON U.S.A. INC. 2009-04-23 US disclosed
US-20090104112-A1 METHOD FOR MAKING MOLECULAR SIEVE SSZ-83 CHEVRON U.S.A. INC. 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10099934-B2 Molecular sieve, COK-5, its synthesis and use SYMPK, DEK, SIK1 TSHR 4841/4885LMNA 3808/4885THRB 4816/4885
US-20180339910-A1 Molecular Sieve, COK-5, Its Synthesis and Use SYMPK, DEK, SIK1 TSHR 4841/4885LMNA 3808/4885THRB 4816/4885
US-20160023914-A1 Molecular Sieve, COK-5, Its Synthesis and Use SYMPK, DEK, SIK1 TSHR 4841/4885LMNA 3808/4885THRB 4816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.