Sugi Predict
/ Targets
/ SYMPK
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to SYMPK by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| Effect of Montelukast Therapy on Clinical Course, Pulmonary Function, and Mortality in Patients With COVID-19 |
PHASE4 | UNKNOWN |
| Effect of Add-on Montelukast to Inhaled Corticosteroids on Airway Responsiveness |
PHASE4 | COMPLETED |
| Effects of NSK-SD (Nattokinase) on Blood Pressure |
PHASE4 | COMPLETED |
| Safety & Efficacy of Zirconium Silicate in Mild to Moderate Hyperkalemia |
PHASE3 | COMPLETED |
| Reduce Incidence of Pre-Dialysis Hyperkalaemia With Sodium Zirconium Cyclosilicate in Chinese Subjects |
PHASE3 | COMPLETED |
| Safety & Efficacy of Zirconium Silicate Dosed for 28 Days in Hyperkalemia. |
PHASE3 | COMPLETED |
| Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Patients With MFS |
PHASE3 | COMPLETED |
| A Phase Ⅲ Efficacy and Safety Study of Hemay005 in Subjects With Moderate to Severe Plaque Psoriasis |
PHASE3 | COMPLETED |
| A Study of Guselkumab in Participants With Active Psoriatic Arthritis and an Inadequate Response to Anti-Tumor Necrosis Factor Alpha (Anti-TNF Alpha) Therapy |
PHASE3 | COMPLETED |
| Six Months Efficacy and Safety of Aliskiren Therapy on Top of Standard Therapy, on Morbidity and Mortality in Patients With Acute Decompensated Heart Failure |
PHASE3 | COMPLETED |
| A Phase 3 Clinical Study of KHK 4827 |
PHASE3 | COMPLETED |
| OPtimizing Aldosterone Receptor Antagonist Therapy by Sodium Zirconium Cyclosili-cate in Heart Failure -Extension (OPRA-HF Extension) |
PHASE2 | NOT_YET_RECRUITING |
| Study to Assess the Safety and Efficacy of SelK2 on Airway Responses Following Allergen Challenge in Subjects With Asthma (Part 1) and in Subjects With Chronic Obstructive Pulmonary Disease (Part 2) |
PHASE2 | COMPLETED |
| Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis |
PHASE2 | ACTIVE_NOT_RECRUITING |
| A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Plaque Psoriasis |
PHASE2 | COMPLETED |
| Evaluation of the Efficacy of Bio-K+ Cl-1285® In the Nasal Decolonization of Methicillin Resistant Staphylococcus Aureus (MRSA) Carrier Patients |
PHASE2 | WITHDRAWN |
| An Open-Label Study to Investigate the Safety of Single and Multiple Ascending Doses in Children and Adolescents With Dravet Syndrome |
PHASE1/PHASE2 | COMPLETED |
| Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers |
PHASE2 | NOT_YET_RECRUITING |
| A Study Evaluating the Efficacy and Safety of HSK21542 Injection for Analgesia in Subjects Undergoing Colonoscopy |
PHASE2 | COMPLETED |
| An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy |
PHASE2 | COMPLETED |
| An Open-Label Extension Study of STK-001 for Patients With Dravet Syndrome |
PHASE2 | ACTIVE_NOT_RECRUITING |
| Safety, Tolerability and Pharmacokinetics Study Assessing Ascending Single Oral JTK-853 Doses in Healthy Subjects |
PHASE1 | COMPLETED |
| A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of Oral ZYGK1 in Healthy Volunteers |
PHASE1 | SUSPENDED |
| A Study to Assess Effects of Clarithromycin on Pharmacokinetics of JNJ-54861911 in Healthy Male Participants |
PHASE1 | COMPLETED |
| Plasma and Intrapulmonary Concentrations Study of WCK 5222 |
PHASE1 | COMPLETED |
| To Evaluate the Safety, Tolerability, and Pharmacokinetics After Subcutaneous Administration of C1K in Healthy Subjects |
PHASE1 | COMPLETED |
| A Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Food Effect of PMK-S005 After Oral Administration in Healthy Male Volunteers |
PHASE1 | COMPLETED |
| Pilot Clinical Trial - Comparative Study of Two Material Concentration of OD-141309 |
EARLY_PHASE1 | UNKNOWN |
| A Study of the Absorption, Metabolism, and Excretion of [14C]-SKI-O-703 Following a Single Oral Dose in Healthy Male Subjects |
EARLY_PHASE1 | COMPLETED |
| Assessment of Hyperkalemia's Illness and Treatment Burden in Chronic Kidney Disease and Heart Failure Patients: HK Registry Pilot Study |
nan | COMPLETED |
Related proteins — ESM-2 sequence neighbours (a SYMPK binder may also engage these)