Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.42 |
| ▸ | CHUK | O15111 | 3/20 | 0.42 |
| ▸ | IKBKG | Q9Y6K9 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 6/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCNH | P51946 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 5/20 | 0.40 |
| ▸ | JAK2 | O60674 | 5/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | DKK1 | O94907 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2286487 | 0.89 | CDK2 (0.44) | IKBKBCHUKIKBKGCDK2CDK1 | |
| SCHEMBL2286095 | 0.88 | CDK2 (0.43) | IKBKBCHUKIKBKGCDK2CDK1 | |
| SCHEMBL2286339 | 0.86 | CDK2 (0.46) | IKBKBCHUKIKBKGCDK2CDK1 | |
| SCHEMBL2353118 | 0.86 | JAK2 (0.46) | IKBKBCHUKIKBKGCDK2CDK1 | |
| SCHEMBL2283255 | 0.84 | CDK2 (0.44) | IKBKBCHUKIKBKGCDK2CDK1 | |
| SCHEMBL2278999 | 0.83 | CDK2 (0.43) | IKBKBCHUKIKBKGCDK2CDK1 | |
| SCHEMBL2286079 | 0.83 | CDK2 (0.38) | IKBKBCHUKIKBKGCDK2CDK1 | |
| SCHEMBL2282796 | 0.83 | CDK2 (0.46) | IKBKBCHUKIKBKGCDK2CDK1 | |
| SCHEMBL2285673 | 0.80 | CDK2 (0.63) | CDK2CDK1CDK7CDK9CDK4 | |
| SCHEMBL2283774 | 0.80 | IKBKB (0.41) | IKBKBCHUKIKBKGCDK2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | IKBKB 4725/4885CHUK 4717/4885IKBKG 4638/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | IKBKB 4728/4885CHUK 4722/4885IKBKG 4672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.