Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 14/20 | 0.67 |
| ▸ | HTR1D | P28221 | 2/20 | 0.64 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.64 |
| ▸ | DRD5 | P21918 | 1/20 | 0.64 |
| ▸ | HTR1E | P28566 | 1/20 | 0.64 |
| ▸ | HTR7 | P34969 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.64 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581460 | 1.00 | HTR1F (0.67) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL2537303 | 0.86 | HTR1F (0.71) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL2539945 | 0.84 | HTR1F (0.68) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL2535441 | 0.84 | HTR1F (0.68) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL2540244 | 0.83 | HTR1F (0.81) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL2535443 | 0.83 | HTR1F (0.67) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL2537883 | 0.82 | HTR1F (0.72) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL30908975 | 0.82 | HTR1F (0.72) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| Hydrochloric Acid SCHEMBL2535877 | 0.82 | HTR1F (0.79) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL2535880 | 0.81 | HTR1F (0.78) | HTR1FHTR1DCHRM5DRD5HTR1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117330658-A | HPLC detection method for related substances of key intermediate of lasmidbody | 福建省微生物研究所 | 2024-01-02 | — | — | CN | disclosed |
| CN-117330658-A | HPLC detection method for related substances of key intermediate of lasmidbody | 福建省微生物研究所 | 2024-01-02 | — | — | CN | disclosed |
| EP-3994131-B1 | 2,2-DIMETHYL-N-[6-(1-METHYL-PIPERIDIN-4-CARBONYL)-PYRIDIN-2-YL]-PROPIONAMIDE, METHOD FOR PREPARING (6-AMINO-PYRIDIN-2-YL)-(1-METHYL-PIPERIDIN-4-YL)-METHANONE USING SAID COMPOUND, AND USE OF SAID COMPOUND IN THE PREPARATION OF LASMIDITAN | MOEHS IBERICA SL (ES) | 2023-05-24 | — | — | EP | disclosed |
| US-20220306601-A1 | 2,2-DIMETHYL-N-[6-(1-METHYL-PIPERIDIN-4-CARBONYL)-PYRIDIN-2-YL]-PROPIONAMIDE, METHOD FOR PREPARING (6-AMINO-PYRIDIN-2-YL)-(1-METHYL-PIPERIDIN-4-YL)-METHANONE USING SAID COMPOUND, AND USE OF SAID COMPOUND IN THE PREPARATION OF LASMIDITAN | MOEHS IBERICA, S.L. (ES) | 2022-09-29 | — | — | US | disclosed |
| WO-2021001350-A1 | 2,2-DIMETHYL-N-[6-(1-METHYL-PIPERIDIN-4-CARBONYL)-PYRIDIN-2-YL]-PROPIONAMIDE, METHOD FOR PREPARING (6-AMINO-PYRIDIN-2-YL)-(1-METHYL-PIPERIDIN-4-YL)-METHANONE USING SAID COMPOUND, AND USE OF SAID COMPOUND IN THE PREPARATION OF LASMIDITAN | MOEHS IBERICA, S.L. (ES) | 2021-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306601-A1 | 2,2-DIMETHYL-N-[6-(1-METHYL-PIPERIDIN-4-CARBONYL)-PYRIDIN-2-YL]-PROPIONAMIDE, METHOD FOR PREPARING (6-AMINO-PYRIDIN-2-YL)-(1-METHYL-PIPERIDIN-4-YL)-METHANONE USING SAID COMPOUND, AND USE OF SAID COMPOUND IN THE PREPARATION OF LASMIDITAN | PMP22, PLP2, PTMA | HTR1F 630/4885HTR1D 24/4885CHRM5 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.