Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | PNLIP | P16233 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Horminone SCHEMBL22861891 | 1.00 | CYP19A1 (0.45) | CYP19A1EP300FDPSMEN1USP2 | |
| SCHEMBL30088312 | 0.90 | CYP19A1 (0.45) | CYP19A1EP300FDPSMEN1USP2 | |
| SCHEMBL22472964 | 0.85 | CYP19A1 (0.35) | CYP19A1EP300FDPSMEN1KMT2A | |
| SCHEMBL22861892 | 0.82 | FDPS (0.39) | CYP19A1EP300FDPSGGPS1TP53 | |
| SCHEMBL14303936 | 0.79 | EP300 (0.40) | CYP19A1EP300FDPSGGPS1 | |
| SCHEMBL21291505 | 0.78 | EP300 (0.40) | CYP19A1EP300FDPSMEN1USP2 | |
| Royleanone SCHEMBL16006778 | 0.77 | CYP3A4 (0.44) | CYP19A1EP300FDPSMEN1USP2 | |
| Royleanone SCHEMBL21291506 | 0.77 | CYP3A4 (0.44) | CYP19A1EP300FDPSMEN1USP2 | |
| SCHEMBL22861886 | 0.75 | EP300 (0.38) | CYP19A1EP300FDPSGGPS1 | |
| SCHEMBL22861890 | 0.75 | EP300 (0.38) | CYP19A1EP300FDPSGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210000841-A1 | COMPOUNDS THAT MODULATE VON WILLEBRAND FACTOR LEVELS AND THEIR USE IN THE TREATMENT OF BLOOD DISORDERS | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210000841-A1 | COMPOUNDS THAT MODULATE VON WILLEBRAND FACTOR LEVELS AND THEIR USE IN THE TREATMENT OF BLOOD DISORDERS | F5, F2, F3 | CYP19A1 1873/4885EP300 4632/4885FDPS 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.