SCHEMBL22861986

SCHEMBL22861986

NC(N)Cc1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.56
EPHX1 P07099 1/20 0.52
SRR Q9GZT4 2/20 0.52
PSAT1 Q9Y617 2/20 0.52
IDO1 P14902 2/20 0.50
AGXT P21549 2/20 0.50
SLC6A2 P23975 2/20 0.48
MAOA P21397 1/20 0.48
SLC6A4 P31645 1/20 0.48
SLC6A3 Q01959 1/20 0.48
SIGMAR1 Q99720 1/20 0.48
CYP2A6 P11509 1/20 0.48
ADORA2A P29274 1/20 0.48
ADORA1 P30542 1/20 0.48
ACP3 P15309 1/20 0.47
FFAR1 O14842 1/20 0.47
PPARG P37231 2/20 0.46
PPARA Q07869 2/20 0.46
ABCC4 O15439 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL708446 0.85 EPHX1 (0.70) TAAR1EPHX1SLC6A2MAOASLC6A4
Hydrochloric Acid SCHEMBL15758369 0.82 EPHX1 (0.67) TAAR1EPHX1SRRSLC6A2MAOA
SCHEMBL9417738 0.82 TAAR1 (0.75) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL17413364 0.82 TAAR1 (0.75) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL4075991 0.82 TAAR1 (0.75) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL17887234 0.80 ACP3 (0.51) TAAR1EPHX1SRRPSAT1IDO1
SCHEMBL7357345 0.80 EPHX1 (0.58) TAAR1EPHX1SRRPSAT1IDO1
SCHEMBL7357350 0.80 EPHX1 (0.58) TAAR1EPHX1SRRPSAT1IDO1
SCHEMBL14733400 0.80 EPHX1 (0.58) TAAR1EPHX1SRRPSAT1IDO1
Hydrochloric Acid SCHEMBL27621318 0.80 TAAR1 (0.72) TAAR1SLC6A2MAOASLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021003050-A2 CD38-BINDING AGENTS AND USES THEREOF KLEO PHARMACEUTICALS, INC. (US) 2021-01-07 WO disclosed