Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 4/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862870 | 0.76 | RAD52 (0.37) | RAD52GABRG2GABRB3GABRA5KCNJ1 | |
| SCHEMBL22862520 | 0.74 | GABRG2 (0.36) | GABRG2GABRB3GABRA5KCNJ1DDB1 | |
| SCHEMBL22862779 | 0.65 | TRIM24 (0.40) | RAD52MEN1KMT2A | |
| SCHEMBL29490202 | 0.65 | TRIM24 (0.42) | RAD52MEN1KMT2A | |
| SCHEMBL22862638 | 0.65 | TRIM24 (0.42) | RAD52MEN1KMT2A | |
| SCHEMBL22862953 | 0.65 | TRIM24 (0.42) | RAD52MEN1KMT2A | |
| SCHEMBL29490310 | 0.65 | TRIM24 (0.42) | RAD52MEN1KMT2A | |
| SCHEMBL22862856 | 0.64 | SMN1; SMN2 (0.37) | RAD52PDE1CMEN1KMT2A | |
| SCHEMBL29490177 | 0.64 | SMN1; SMN2 (0.37) | RAD52PDE1CMEN1KMT2A | |
| SCHEMBL22862855 | 0.62 | SMN1; SMN2 (0.37) | PDE1CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021002986-A2 | BAX INHIBITORS AND USES THEREOF | CASE WESTERN RESERVE UNIVERSITY (US) | 2021-01-07 | — | — | WO | disclosed |