Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 7/20 | 0.57 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.57 |
| ▸ | PRKCG | P05129 | 3/20 | 0.57 |
| ▸ | PRKCB | P05771 | 3/20 | 0.57 |
| ▸ | LCK | P06239 | 3/20 | 0.57 |
| ▸ | PRKCA | P17252 | 3/20 | 0.57 |
| ▸ | PRKCH | P24723 | 3/20 | 0.57 |
| ▸ | PRKCI | P41743 | 3/20 | 0.57 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.57 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.57 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.57 |
| ▸ | CDK2 | P24941 | 5/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2286440 | 0.89 | ZAP70 (0.53) | ZAP70PRKD3PRKCGPRKCBLCK | |
| SCHEMBL27741295 | 0.89 | ZAP70 (0.53) | ZAP70PRKD3PRKCGPRKCBLCK | |
| SCHEMBL2282212 | 0.83 | PIK3CG (0.59) | PRKD3PRKCGCDK2EGFRPIK3CA | |
| SCHEMBL2283248 | 0.83 | CDK2 (0.76) | ZAP70PRKD3PRKCGPRKCBLCK | |
| SCHEMBL2282939 | 0.82 | LIMK1 (0.48) | PRKCAEGFRPIK3CAPIK3CGPTK2 | |
| SCHEMBL6975909 | 0.82 | JAK2 (0.70) | ZAP70PRKD3PRKCGPRKCBLCK | |
| SCHEMBL2290262 | 0.82 | CDK2 (0.57) | ZAP70PRKD3PRKCGPRKCBLCK | |
| SCHEMBL2289254 | 0.82 | JAK2 (0.65) | PRKCAPRKCDCDK2EGFRPIK3CA | |
| SCHEMBL2279031 | 0.82 | CDK2 (0.69) | ZAP70PRKD3PRKCGPRKCBLCK | |
| SCHEMBL2282559 | 0.81 | CDK2 (0.61) | ZAP70PRKD3PRKCGPRKCBLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
| CN-101309586-A | Thiazole compounds as fungicides | BAYER CROPSCIENCE AG (DE) | 2008-11-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | ZAP70 1068/4885PRKD3 2889/4885PRKCG 4783/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | ZAP70 1090/4885PRKD3 2951/4885PRKCG 4787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.