Leucine

Leucine

SCHEMBL2286758

CC(C)C[C@H](N)C(=O)O.[NaH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.95
SLC1A2 P43004 7/20 0.71
SLC1A3 P43003 6/20 0.71
SLC1A1 P43005 7/20 0.60
GRIK1 P39086 9/20 0.50
GRIK2 Q13002 6/20 0.50
RNPEP Q9H4A4 1/20 0.48
GRIA2 P42262 2/20 0.47
GRIA4 P48058 2/20 0.47
GRIK3 Q13003 2/20 0.47
GRIK5 Q16478 2/20 0.47
GRIA1 P42261 1/20 0.47
PTGS1 P23219 1/20 0.46
SLC7A11 Q9UPY5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Leucine SCHEMBL6005687 1.00 SLC7A5 (0.95) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL27358635 1.00 SLC7A5 (0.95) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL4594997 0.97 SLC7A5 (0.90) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL2478164 0.97 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL20362356 0.97
Leucine SCHEMBL25241602 0.97 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL8568060 0.97 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL331557 0.97 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL3888 0.97
D-Leucine SCHEMBL42012 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240075457-A1 METHOD OF FORMING INTEGRATED COMPOSITE COMPRISING CONDUCTIVE CARBON NETWORK SUSTAERA INC (US) 2024-03-07 US claimed
CN-109665917-A Suitable for the liquid suspension set meal fertilizer of solanaceous vegetables and its preparation and method of administration 福建省农业科学院土壤肥料研究所 2019-04-23 CN claimed
CN-109430535-A A kind of preparation method of feed addictive branched-chain amino acid 长沙道勤生物科技有限公司 2019-03-08 CN claimed
CN-108244153-A Promote increasing agent of tall scrawny person and preparation method thereof 金华市铁骑士生物科技有限公司 2018-07-06 CN claimed
CN-108135962-A For the pharmaceutical preparation of oral delivery peptide medicament 塞浦路迈德有限责任公司 2018-06-08 CN claimed
CN-106794252-A Pharmaceutical formulations for oral delivery of peptide or protein drugs 塞浦路迈德有限责任公司 2017-05-31 CN claimed
CN-105010343-B Sprouting vegetable yield increasing agent and preparation method thereof 武汉市农业科学研究所 2017-04-19 CN claimed
CN-105924272-A Amino-acid-containing medium-element water-soluble discoloration fertilizer and dilution control method therefor 纪新强 2016-09-07 CN claimed
CN-105906429-A Liquid water-soluble color-changing fertilizer containing amino acid and trace element and dilution control method of fertilizer 纪新强 2016-08-31 CN claimed
CN-105906428-A Liquid water-soluble color-changing fertilizer containing amino acid and medium element and dilution control method of fertilizer 纪新强 2016-08-31 CN claimed
CN-103458873-B For the aminoacid of the fatty-acylation of oral peptide delivery NOVO NORDISK A/S (DK) 2016-04-13 CN claimed
CN-105010343-A Sprouting vegetable yield increasing agent and preparation method thereof WUHAN INST OF AGRICULTURAL SCIENCE 2015-11-04 CN claimed
CN-104607098-A Method for preparing grease acyl sodium leucine and surface active agent composition containing grease acyl sodium leucine in phase-transfer catalysis way UNIV BEIJING TECH & BUSINESS 2015-05-13 CN claimed
CN-102552283-B Transdermal absorption drug for skin prepared from hydrocortisone butyrate containing adjuvant and water containing adjuvant TIANJIN JINYAO GROUP CO LTD 2015-03-18 CN claimed
CN-103664687-A Synthesis method of 2-((3,5-di-tertiary butyl benzal) amino) - 4 - methyl pentanoic acid XUZHOU RUISAI TECHNOLOGY IND CO LTD 2014-03-26 CN claimed
CN-103458873-A Fatty acid acylated amino acids for oral peptide delivery NOVO NORDISK AS 2013-12-18 CN claimed
CN-101597276-B Propylidene derivative of N-(Alpha, Beta-dimercapto-Beta-carboxyl propionyl)-amino acid and synthetic method and application thereof UNIV BEIJING 2012-03-28 CN claimed
CN-101597276-A N-(α, Beta-dimercapto base-β-carboxypropanoyl)-amino acid whose propylidene derivative and synthetic method and application UNIV BEIJING (CN) 2009-12-09 CN claimed
CN-1883305-A Method for preparing seasonings by combination of peony natural organic compounds ZHANG YINGQIANG (CN) 2006-12-27 CN claimed
CN-1264581-A Medicine for reducing vaginal acidity and its usage ZENG ZHONGMING (CN) 2000-08-30 CN claimed