Leucine

Leucine

SCHEMBL2478164

CC(C)CC(N)C(=O)O.CC(C)C[C@H](N)C(=O)O.CC(C)C[C@H](N)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 1.00
SLC1A2 P43004 7/20 0.74
SLC1A3 P43003 6/20 0.74
SLC1A1 P43005 7/20 0.62
GRIK1 P39086 9/20 0.52
GRIK2 Q13002 6/20 0.52
RNPEP Q9H4A4 1/20 0.50
GRIA2 P42262 2/20 0.48
GRIA4 P48058 2/20 0.48
GRIK3 Q13003 2/20 0.48
GRIK5 Q16478 2/20 0.48
GRIA1 P42261 1/20 0.48
PTGS1 P23219 1/20 0.48
SLC7A11 Q9UPY5 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Leucine SCHEMBL175940 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL8568063 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
D-Leucine SCHEMBL9449950 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL20362356 1.00
Leucine SCHEMBL3888 1.00
D-Leucine SCHEMBL42012 1.00
Leucine SCHEMBL25241602 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL8568060 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL331557 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
D-Leucine SCHEMBL9100148 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1666023-B1 Improvements in and relating to carrier particles for use in dry powder inhalers VECTURA LTD (GB) 2011-10-05 EP disclosed