Sugi Predict

Sugi Predict / Compounds / SCHEMBL2286785

SCHEMBL2286785

SCHEMBL2286785

C#CCOc1c(F)cc(C(=O)NC2CCCCC2N)cc1F

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TAS1R3 Q7RTX0 6/20 0.41
▸ TAS1R1 Q7RTX1 6/20 0.41
▸ TAS1R2 Q8TE23 6/20 0.41
▸ HDAC4 P56524 1/20 0.39
▸ MMP2 P08253 2/20 0.37
▸ MMP9 P14780 2/20 0.37
▸ CA12 O43570 2/20 0.37
▸ CA1 P00915 2/20 0.37
▸ CA2 P00918 2/20 0.37
▸ CA9 Q16790 2/20 0.37
▸ MMP1 P03956 1/20 0.37
▸ MMP3 P08254 1/20 0.37
▸ MMP8 P22894 1/20 0.37
▸ MMP13 P45452 1/20 0.37
▸ SSTR3 P32745 5/20 0.37
▸ CHRNA7 P36544 1/20 0.36
▸ PARP1 P09874 1/20 0.35
▸ NTRK1 P04629 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4247557 0.87 TAS1R3 (0.42) TAS1R3TAS1R1TAS1R2SSTR3CHRNA7
SCHEMBL4249309 0.87 CNR1 (0.44) TAS1R3TAS1R1TAS1R2
SCHEMBL4246193 0.86 TAS1R3 (0.58) TAS1R3TAS1R1TAS1R2
SCHEMBL2287117 0.86 TAS1R3 (0.44) TAS1R3TAS1R1TAS1R2SSTR3CHRNA7
SCHEMBL4241681 0.86 TAS1R3 (0.41) TAS1R3TAS1R1TAS1R2SSTR3CHRNA7
SCHEMBL4247030 0.86 TAS1R3 (0.58) TAS1R3TAS1R1TAS1R2
SCHEMBL4245689 0.86 TAS1R3 (0.41) TAS1R3TAS1R1TAS1R2SSTR3CHRNA7
SCHEMBL4246190 0.86 TAS1R3 (0.58) TAS1R3TAS1R1TAS1R2
SCHEMBL4248445 0.86 TAS1R3 (0.41) TAS1R3TAS1R1TAS1R2SSTR3CHRNA7
SCHEMBL2282159 0.85 TAS1R3 (0.40) TAS1R3TAS1R1TAS1R2SSTR3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003699-B2 Amide compound and use thereof for controlling plant diseases SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-23 — — US disclosed
US-8003699-B2 Amide compound and use thereof for controlling plant diseases SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-23 — — US disclosed
US-8003699-B2 Amide compound and use thereof for controlling plant diseases SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-23 — — US disclosed
US-20100105647-A1 AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES SUMITOMO CHEMICAL COMPANY, LIMITED 2010-04-29 — — US disclosed
US-20100105647-A1 AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES SUMITOMO CHEMICAL COMPANY, LIMITED 2010-04-29 — — US disclosed
US-20100105647-A1 AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES SUMITOMO CHEMICAL COMPANY, LIMITED 2010-04-29 — — US disclosed
EP-2151432-A1 AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES Sumitomo Chemical Company, Limited (JP) 2010-02-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105647-A1 AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES CYC1, CBR3, CBR1 TAS1R3 2625/4885TAS1R1 1944/4885TAS1R2 2066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.