SCHEMBL22868650

SCHEMBL22868650

CC1(C)c2ccccc2-c2c1ccc1cc(-c3nc(-c4ccccc4)c4ccccc4n3)ccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
ATM Q13315 2/20 0.45
WHR1 P49842 1/20 0.40
NUDT1 P36639 3/20 0.36
ADORA2A P29274 3/20 0.35
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.34
NR1I3 Q14994 3/20 0.34
MAPT P10636 3/20 0.34
RAD52 P43351 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
VDR P11473 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2B6 P20813 1/20 0.34
AHR P35869 1/20 0.34
PDE10A Q9Y233 1/20 0.34
GAA P10253 1/20 0.33
AURKA O14965 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24275545 0.94 MEN1 (0.42) MEN1KMT2AATMWHR1NUDT1
SCHEMBL24274978 0.93 MEN1 (0.43) MEN1KMT2AATMWHR1NUDT1
SCHEMBL22868563 0.92 MEN1 (0.46) MEN1KMT2AATMWHR1NUDT1
SCHEMBL22868927 0.89 MEN1 (0.42) MEN1KMT2AATMWHR1NUDT1
SCHEMBL22868567 0.89 MAPT (0.35) MEN1KMT2AATMWHR1ADORA2A
SCHEMBL22868565 0.88 CYP1A1 (0.34) MEN1KMT2AATMWHR1ADORA2A
SCHEMBL22868667 0.88 MEN1 (0.47) MEN1KMT2AATMWHR1NUDT1
SCHEMBL22869025 0.88 ATM (0.38) MEN1KMT2AATMWHR1ADORA2A
SCHEMBL22868783 0.87 ESR1 (0.36) MEN1KMT2AATMWHR1ADORA2A
SCHEMBL22868898 0.86 MEN1 (0.43) MEN1KMT2AATMWHR1NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210005822-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-07 US disclosed