SCHEMBL22868565

SCHEMBL22868565

CC1(C)c2ccccc2-c2c1ccc1cc(-c3nc(-c4ccccc4)c4ccc5ccccc5c4n3)ccc21

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP1B1 Q16678 1/20 0.34
WHR1 P49842 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
MAOA P21397 1/20 0.32
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
MAPT P10636 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SOS1 Q07889 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22868561 0.95 CYP1A1 (0.35) CYP1A1CYP1A2CYP1B1WHR1MEN1
SCHEMBL22868899 0.88 ALDH1A1 (0.32) CYP1A1CYP1A2CYP1B1MEN1KMT2A
SCHEMBL22868650 0.88 MEN1 (0.45) CYP1A2WHR1MEN1KMT2AATM
SCHEMBL22186236 0.88 CYP1A1 (0.32) CYP1A1CYP1A2CYP1B1MEN1KMT2A
SCHEMBL22868568 0.87 CYP1A1 (0.34) CYP1A1CYP1A2CYP1B1WHR1MEN1
SCHEMBL22868567 0.86 MAPT (0.35) CYP1A2WHR1MEN1KMT2AATM
SCHEMBL22869015 0.85 MEN1 (0.35) CYP1A1CYP1A2CYP1B1WHR1MEN1
SCHEMBL22868732 0.85 CYP1A1 (0.34) CYP1A1CYP1A2CYP1B1WHR1MEN1
SCHEMBL22868807 0.85 SOS1 (0.35) CYP1A1CYP1A2CYP1B1MEN1KMT2A
SCHEMBL22868783 0.84 ESR1 (0.36) CYP1A2WHR1MEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210005822-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-07 US disclosed