Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154431 | 0.85 | BACE1 (0.50) | TAAR1BACE1ALDH1A1MAPTPOLB | |
| SCHEMBL11855440 | 0.83 | BACE1 (0.46) | TAAR1BACE1ALDH1A1MAPTPOLB | |
| SCHEMBL9309388 | 0.81 | SKP2 (0.48) | BACE1ALDH1A1MAPTPOLBTP53 | |
| SCHEMBL20081763 | 0.81 | HRH3 (0.54) | HRH3TAAR1HTR7HTR1AALDH1A1 | |
| SCHEMBL394746 | 0.78 | ALDH1A1 (0.48) | TAAR1BACE1ALDH1A1MAPTPOLB | |
| SCHEMBL27798768 | 0.78 | SKP2 (0.59) | HRH3TAAR1HTR7ALDH1A1MAPT | |
| SCHEMBL23092976 | 0.78 | SKP2 (0.65) | BACE1HTR1AALDH1A1MAPTPOLB | |
| SCHEMBL237448 | 0.77 | ALDH1A1 (0.50) | BACE1ALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL15175048 | 0.76 | SKP2 (0.58) | ALDH1A1TP53SKP2SLC6A2SLC6A4 | |
| SCHEMBL20081762 | 0.76 | TAAR1 (0.55) | HRH3TAAR1HTR7ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003339-A1 | AMP-ACTIVATED PROTEIN KINASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2021-01-07 | — | — | WO | disclosed |