Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 7/20 | 0.42 |
| ▸ | ACACB | O00763 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581152 | 1.00 | ACACA (0.42) | ACACAACACBKMT2APOLBHTT | |
| SCHEMBL28683936 | 1.00 | ACACA (0.42) | ACACAACACBKMT2APOLBHTT | |
| SCHEMBL22870047 | 1.00 | ACACA (0.42) | ACACAACACBKMT2APOLBHTT | |
| SCHEMBL21570681 | 0.86 | ACACA (0.43) | ACACAACACBKMT2APOLBHTT | |
| SCHEMBL21570639 | 0.84 | ACACA (0.43) | ACACAACACBKMT2APOLBHTT | |
| SCHEMBL21570598 | 0.84 | ACACA (0.45) | ACACAACACBKMT2APOLBHTT | |
| SCHEMBL22283796 | 0.83 | ACACB (0.47) | ACACAACACB | |
| SCHEMBL22144396 | 0.83 | ACACB (0.47) | ACACAACACB | |
| SCHEMBL24404214 | 0.80 | ACACA (0.42) | ACACAACACBPOLBHTTNPSR1 | |
| SCHEMBL24404173 | 0.80 | ACACA (0.42) | ACACAACACBPOLBHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3995498-A1 | THIENOPYRIMIDINE DERIVATIVES HAVING STEREO CONFIGURATIONS AND USE THEREOF IN MEDICINE | Sunshine Lake Pharma Co., Ltd. (CN) | 2022-05-11 | — | — | EP | disclosed |
| CN-113924303-A | Thienopyrimidine derivatives with spatial configuration and application thereof in medicines | 广东东阳光药业有限公司 | 2022-01-11 | — | — | CN | disclosed |
| WO-2021000242-A1 | THIENOPYRIMIDINE DERIVATIVES HAVING STEREO CONFIGURATIONS AND USE THEREOF IN MEDICINE | 广东东阳光药业有限公司 | 2021-01-07 | — | — | WO | disclosed |