Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24656113 | 0.77 | HTT (0.41) | ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL14666982 | 0.77 | ENPP2 (0.44) | LMNAENPP2ALOX15 | |
| SCHEMBL19489957 | 0.74 | DPP4 (0.39) | ESR1ESR2 | |
| SCHEMBL18967229 | 0.71 | ENPP2 (0.37) | ENPP2ALDH1A1ALOX15TSHRMAPK1 | |
| SCHEMBL12447340 | 0.69 | GRIN2D (0.39) | ALOX15ESR1ESR2 | |
| SCHEMBL6817121 | 0.69 | DPP4 (0.46) | — | |
| SCHEMBL16029817 | 0.67 | ENPP2 (0.37) | ENPP2 | |
| SCHEMBL22871836 | 0.67 | ENPP2 (0.33) | ENPP2ALDH1A1ALOX15 | |
| SCHEMBL22366951 | 0.67 | ENPP2 (0.33) | ENPP2 | |
| SCHEMBL24984321 | 0.67 | ENPP2 (0.33) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10889611-B2 | Sialyltransferase inhibitors and uses thereof | ACADEMIA SINICA (TW) | 2021-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10889611-B2 | Sialyltransferase inhibitors and uses thereof | ST6GAL1, NEU1, GALNT1 | LMNA 4496/4885ENPP2 50/4885ALDH1A1 1642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.