Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PPIA | P62937 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29273709 | 0.88 | MAPT (0.65) | KMT2AMEN1LMNAPPIAMAPT | |
| SCHEMBL16593178 | 0.81 | KMT2A (0.56) | KMT2AMEN1LMNAPPIAMAPT | |
| SCHEMBL13480594 | 0.80 | PPIA (0.61) | KMT2AMEN1LMNAPPIAMAPT | |
| SCHEMBL18007197 | 0.80 | KMT2A (0.56) | KMT2AMEN1LMNAPPIAMAPT | |
| SCHEMBL144326 | 0.80 | KMT2A (0.65) | KMT2AMEN1LMNAPPIAMAPT | |
| SCHEMBL13969504 | 0.78 | KMT2A (0.53) | KMT2AMEN1LMNAPPIAMAPT | |
| SCHEMBL16592358 | 0.78 | CA12 (0.63) | KMT2AMEN1PPIAMAPTTSHR | |
| SCHEMBL1007576 | 0.78 | MAPT (0.62) | KMT2AMEN1LMNAPPIAMAPT | |
| SCHEMBL1567605 | 0.78 | KMT2A (0.61) | KMT2AMEN1LMNAPPIAMAPT | |
| SCHEMBL27817518 | 0.78 | NTRK1 (0.59) | KMT2AMEN1LMNAPPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021004391-A1 | C-MYC PROTEIN INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州开拓药业股份有限公司 | 2021-01-14 | — | — | WO | disclosed |