Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 19/20 | 0.77 |
| ▸ | HDAC1 | Q13547 | 19/20 | 0.77 |
| ▸ | HDAC2 | Q92769 | 19/20 | 0.77 |
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.77 |
| ▸ | VNN1 | O95497 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632500 | 0.87 | HDAC3 (1.00) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL16644415 | 0.87 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL21698898 | 0.86 | HDAC3 (0.75) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL16644351 | 0.78 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL16632303 | 0.77 | HDAC3 (1.00) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22874123 | 0.77 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL22874169 | 0.76 | HDAC3 (0.75) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22874116 | 0.75 | HDAC3 (0.72) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL16632448 | 0.75 | HDAC3 (1.00) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL19710840 | 0.74 | VNN1 (0.61) | HDAC3HDAC1HDAC2HDAC6VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055299-B1 | PYRIMIDINE HYDROXY AMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | ACETYLON PHARMACEUTICALS INC (US) | 2021-01-06 | — | — | EP | disclosed |