SCHEMBL2287476

SCHEMBL2287476

FCc1ccccc1I

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17151873 0.79 TAAR1 (0.67)
SCHEMBL1538555 0.78 HSPA5 (0.45)
SCHEMBL29712515 0.78 HSPA5 (0.45)
SCHEMBL29118640 0.77 TAAR1 (0.37)
SCHEMBL29118645 0.77 TAAR1 (0.33)
SCHEMBL1228231 0.76 IDO1 (0.67)
SCHEMBL6643892 0.76 TSHR (0.42)
SCHEMBL28812083 0.75 TAAR1 (0.61)
SCHEMBL2043471 0.74
SCHEMBL284465 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107739380-A A kind of acridine derivatives and preparation method thereof 陕西莱特光电材料股份有限公司 2018-02-27 CN claimed
CN-117500785-A Azetidinyl-containing carboxylic acid compounds for the treatment of neurodegenerative diseases 细胞基因公司 2024-02-02 CN disclosed
CN-108530241-A A kind of preparation method of Benzocyclodirivative and Eptazocine with benzyl position quaternary carbon center 武汉大学 2018-09-14 CN disclosed
CN-107987034-A Preparation method of dibenzo [ c, e ] [1,2] thiazine-5-oxo series compound with tricyclic system structure 江西师范大学 2018-05-04 CN disclosed
CN-107739380-A A kind of acridine derivatives and preparation method thereof 陕西莱特光电材料股份有限公司 2018-02-27 CN disclosed
EP-2149545-B1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2016-10-05 EP disclosed
CN-103874493-A Inhibitors of the renal outer medullary potassium channel MERCK SHARP & DOHME 2014-06-18 CN disclosed
CN-101679172-B Method for producing benzaldehyde compound SUMITOMO CO LTD 2013-05-29 CN disclosed
US-7994367-B2 Method for producing benzaldehyde compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-09 US disclosed
US-20100210879-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-19 US disclosed
CN-101679172-A Method for producing benzaldehyde compound SUMITOMO CHEMICAL CO 2010-03-24 CN disclosed
EP-2149545-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-02-03 EP disclosed
EP-1159314-B1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEM CO (US) 2004-08-04 EP disclosed
CN-1138793-C Process for producing polyethylene �Ϻ���ͨ��ѧ 2004-02-18 CN disclosed
US-6534613-B2 Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst EASTMAN CHEMICAL COMPANY 2003-03-18 US disclosed
CN-1332753-A Process for producing polyethylene EASTMAN CHEM CO (US) 2002-01-23 CN disclosed
US-20020007024-A1 Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst WESTLAKE LONGVIEW CORPORATION 2002-01-17 US disclosed
EP-1159314-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2001-12-05 EP disclosed
WO-2000052067-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed