⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5350956 | 0.81 | HSPA5 (0.38) | — | |
| SCHEMBL172963 | 0.80 | — | — | |
| SCHEMBL9642112 | 0.78 | TAAR1 (0.62) | — | |
| SCHEMBL12086036 | 0.78 | TAAR1 (0.50) | — | |
| SCHEMBL284465 | 0.77 | — | — | |
| Methylamine SCHEMBL11265851 | 0.76 | TAAR1 (0.54) | — | |
| SCHEMBL16946507 | 0.74 | — | — | |
| SCHEMBL2287476 | 0.74 | — | — | |
| SCHEMBL172901 | 0.74 | — | — | |
| SCHEMBL1445634 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104136416-B | Phenylalkylamino carbamate derivatives compound and comprise the pharmaceutical composition of this Phenylalkylamino carbamate derivatives compound | 比皮艾思药物研发有限公司 | 2016-11-09 | — | — | CN | claimed |
| CN-105209027-A | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes | BIO PHARM SOLUTIONS CO LTD | 2015-12-30 | — | — | CN | claimed |
| CN-104136416-A | Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same | BIO PHARM SOLUTIONS CO LTD | 2014-11-05 | — | — | CN | claimed |
| CN-114478211-B | Preparation method of etazocine intermediate | 广州一品红制药有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-114478213-B | Method for preparing etazocine intermediate by utilizing micro-channel device | 广州一品红制药有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-115521276-B | F-18 marked chiral pure derivative of hydroxyfuran and preparation method and application thereof | 中山大学附属第一医院 | 2023-03-10 | — | — | CN | disclosed |
| CN-115521276-A | F-18 marked chiral pure derivative of hydroxyfuran and preparation method and application thereof | 中山大学附属第一医院 | 2022-12-27 | — | — | CN | disclosed |
| CN-114478211-A | Preparation method of eptazocine intermediate | 广州一品红制药有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478213-A | Method for preparing eptazocine intermediate by using microchannel device | 广州一品红制药有限公司 | 2022-05-13 | — | — | CN | disclosed |
| EP-3059235-B1 | TETRAZOLINONE DERIVATIVES AND THEIR USE FOR CONTROLLING PESTS | SUMITOMO CHEMICAL CO (JP) | 2020-10-28 | — | — | EP | disclosed |
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |
| EP-1404335-A1 | AMINO NICOTINATE DERIVATIVES AS GLUCOKINASE (GLK) MODULATORS | Astrazeneca AB (SE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003000267-A1 | AMINO NICOTINATE DERIVATIVES AS GLUCOKINASE (GLK) MODULATORS | ASTRAZENECA AB (SE) | 2003-01-03 | — | — | WO | disclosed |
| CN-1093536-C | 5-lipoxygenase inhibitors | PFIZER (US) | 2002-10-30 | — | — | CN | disclosed |
| US-6166036-A | Lp(a)-lowering agent and apolipoprotein (a) formation suppressing agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-1000620-A1 | Lp(a)-LOWERING AGENTS AND APOPROTEIN (a) PRODUCTION INHIBTORS | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-05-17 | — | — | EP | disclosed |
| CN-1169722-A | 5-lipoxygenase inhibitors | PFIZER (US) | 1998-01-07 | — | — | CN | disclosed |
| EP-0393607-B1 | Phenylcarboxylic acid derivatives having a hetero ring | OTSUKA PHARMA CO LTD (JP) | 1996-02-21 | — | — | EP | disclosed |
| US-5145865-A | Fatty acid, cholesterol synthesis inhibitors; enzyme inhibitors; antilipemic agents | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0393607-A2 | Phenylcarboxylic acid derivatives having a hetero ring | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |