Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21949134 | 0.69 | GRIA1 (0.78) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL19068666 | 0.69 | ALDH1A1 (0.70) | PSMB8GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL15730579 | 0.64 | GRIA1 (0.68) | RXFP1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL18358719 | 0.64 | PSMB8 (0.44) | PSMB8NPSR1RXFP1ALDH1A1MAPT | |
| SCHEMBL2270592 | 0.64 | GRIN2D (0.39) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL18358720 | 0.62 | PSMB8 (0.58) | PSMB8NPSR1RXFP1ALDH1A1MEN1 | |
| SCHEMBL29212232 | 0.62 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL11389872 | 0.61 | ALDH1A1 (0.33) | ALDH1A1APOBEC3GCYP3A4 | |
| SCHEMBL5769722 | 0.60 | GRIN2D (1.00) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL1440205 | 0.60 | GRIN2D (0.76) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3763706-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-01-13 | — | — | EP | disclosed |