SCHEMBL22875444

SCHEMBL22875444

CCCCCCCCCCCCCCC(=O)O[C@H]1C[C@H](n2cnc3c(=O)[nH]c(N)nc32)O[C@@H]1COP(=O)(OCCCCCCCCCCCC)OCCCCCCCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.52
▸ F2 P00734 1/20 0.46
▸ FUT5 Q11128 1/20 0.46
▸ P2RY2 P41231 1/20 0.45
▸ P2RY4 P51582 1/20 0.45
▸ P2RY6 Q15077 1/20 0.45
▸ NT5E P21589 1/20 0.44
▸ KRAS P01116 3/20 0.44
▸ TAS1R3 Q7RTX0 1/20 0.43
▸ TAS1R1 Q7RTX1 1/20 0.43
▸ HINT1 P49773 3/20 0.43
▸ P2RY1 P47900 1/20 0.42
▸ PNP P00491 1/20 0.42
▸ TGM2 P21980 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22875452 1.00 POLB (0.52) POLBF2FUT5P2RY2P2RY4
SCHEMBL5352518 0.89 HINT1 (0.50) POLBF2FUT5P2RY2P2RY4
SCHEMBL5355041 0.89 HINT1 (0.50) POLBF2FUT5P2RY2P2RY4
SCHEMBL8447610 0.89 HINT1 (0.50) POLBF2FUT5P2RY2P2RY4
SCHEMBL22875468 0.89 HINT1 (0.50) POLBF2FUT5P2RY2P2RY4
SCHEMBL22875445 0.88 POLB (0.67) POLBF2FUT5P2RY2P2RY4
SCHEMBL5351509 0.87 KDM4E (0.49) POLBFUT5HINT1
SCHEMBL5351515 0.87 KDM4E (0.49) POLBFUT5HINT1
SCHEMBL22875579 0.86 POLB (0.49) POLBP2RY2TAS1R3TAS1R1P2RY1
SCHEMBL22930760 0.86 POLB (0.49) POLBF2FUT5P2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210007999-A1 NANOPARTICLE COMPOSITIONS JANUARY THERAPEUTICS, INC. 2021-01-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210007999-A1 NANOPARTICLE COMPOSITIONS PNP, NTPCR, TYMP POLB 908/4885F2 4103/4885FUT5 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback