Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15024192 | 0.88 | SLC22A1 (0.70) | SLC22A1OPRM1AOC3TAAR1ACP3 | |
| SCHEMBL13886378 | 0.88 | SLC22A1 (0.70) | SLC22A1OPRM1AOC3TAAR1ACP3 | |
| SCHEMBL12311676 | 0.88 | SLC22A1 (0.70) | SLC22A1OPRM1AOC3TAAR1ACP3 | |
| SCHEMBL15471670 | 0.78 | SLC22A1 (0.49) | SLC22A1OPRM1AOC3TAAR1ACP3 | |
| SCHEMBL15471682 | 0.78 | SLC22A1 (0.45) | SLC22A1OPRM1AOC3TAAR1CYP19A1 | |
| SCHEMBL15471683 | 0.78 | SLC22A1 (0.45) | SLC22A1OPRM1AOC3TAAR1CYP19A1 | |
| SCHEMBL28105608 | 0.75 | SLC22A1 (0.41) | SLC22A1OPRM1AOC3TAAR1CYP19A1 | |
| SCHEMBL6411376 | 0.75 | SLC22A1 (0.70) | SLC22A1OPRM1AOC3SLC6A2SLC6A4 | |
| SCHEMBL15471658 | 0.72 | OPRM1 (0.43) | SLC22A1OPRM1AOC3ACP3ACHE | |
| SCHEMBL14683339 | 0.72 | OPRM1 (0.43) | SLC22A1OPRM1AOC3ACP3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377049-B1 | CRYSTALLINE FORMS OF TAPENTADOL SALTS AND PROCESS FOR PREPARATION THEREOF | MSN LABORATORIES PRIVATE LTD (IN) | 2021-01-06 | — | — | EP | disclosed |