SCHEMBL22876110

SCHEMBL22876110

c1ccc(-c2nc(-c3cccc(-c4cccc5oc6ccc(-c7ccc8c(ccc9ccccc98)c7)cc6c45)c3)nc(-c3cccc4c3sc3ccccc34)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.38
PRKDC P78527 2/20 0.36
MAPT P10636 4/20 0.35
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 2/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.35
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
KMT2A Q03164 2/20 0.33
MAPK1 P28482 2/20 0.33
PLA2G10 O15496 1/20 0.33
PLA2G2A P14555 1/20 0.33
PLA2G4A P47712 1/20 0.33
LIMK1 P53667 2/20 0.32
S1PR5 Q9H228 5/20 0.32
S1PR4 O95977 4/20 0.32
TP53 P04637 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19802560 0.97 ALOX5 (0.36) ALOX5PRKDCMAPTKDM4EALDH1A1
SCHEMBL23822594 0.96 ALOX5 (0.38) ALOX5PRKDCMAPTKDM4EALDH1A1
SCHEMBL19802317 0.96 ALOX5 (0.39) ALOX5PRKDCMAPTKDM4EALDH1A1
SCHEMBL19802621 0.94 ALOX5 (0.38) ALOX5PRKDCMAPTKDM4EALDH1A1
SCHEMBL19802322 0.93 ALOX5 (0.39) ALOX5PRKDCMAPTKDM4EALDH1A1
SCHEMBL19802555 0.93 ALOX5 (0.41) ALOX5PRKDCPLA2G10PLA2G2APLA2G4A
SCHEMBL19802626 0.92 MAPK1 (0.35) ALOX5MAPTKDM4EALDH1A1HPGD
SCHEMBL19802565 0.92 MAPK1 (0.35) ALOX5MAPTKDM4EALDH1A1HPGD
SCHEMBL23822603 0.92 ALOX5 (0.43) ALOX5PRKDCPLA2G10PLA2G2APLA2G4A
SCHEMBL19802173 0.91 ALOX5 (0.38) ALOX5PRKDCMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685859-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-06-27 US disclosed
US-11685859-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-06-27 US disclosed
US-20210009894-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-14 US disclosed